SPR Applications

Enhanced Surface Plasmon Resonance (E-SPR) high performance biosensors from BiOptix are powerful tools that are capable of providing information on kinetic processes (association and dissociation), binding affinities, analyte concentrations and real-time molecule detection. A wide variety of biomolecular interactions can be monitored including the applications listed below.

Biological Applications

  • Protein-small molecule interactions
  • Protein-protein interactions
  • Antibody-antigen interactions
  • Kinetics & affinities
  • Affinity maturation
  • Epitope binning
  • Nucleic acid-protein interactions
  • Biomolecule concentration measurements


Measuring binding kinetics and affinity of small molecule drugs and biologics to their targets is critical to drug development, providing key insights on pharmacodynamics, pharmacokinetics, dosing regimens, and efficacy. In this webinar, scientists from CytomX Therapeutics and SomaLogic highlight multiple biophysical applications of the use of surface plasmon resonance (SPR) biosensors, and the BiOptix 404pi specifically, in drug discovery research.

For additional information please contact a BiOptix product specialist at: 303-545-5550 ext. 103 or info@bioptix.com.

BiOptix: Kinetics with Confidence.